For a single home PC, I'd say don't bother.
If you control a network of 30 computers with decent cards and won't get questioned about electricity bills or hardware meltdowns, maybe try your luck.
I mine in a pool, as finding a coin mining by yourself is incredibly, incredibly unlikely. Of course, you'd bag 25 full coins for yourself (which now would be maybe £15k?) but you're probably as likely to win the lottery.
In a pool you mine with a load of other people, and winnings are split between all participants based on their contribution of blocks. It's a small payout, but it's something as opposed to the nothing you may get forever by mining alone.
The pool I use, should you care, is Slush's pool: https://mining.bitcoin.cz
Fairly well implemented, hosted on Amazon's AWS, and the guy running it has made it, over time, fairly resilient against the huge volume of DoS and intrusion attempts that have inevitably been made on it. The guy must be fucking loaded because the pool takes a nice cut from every block found.